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Lack of immunoglobulin A1 protease production by Haemophilus ducreyi
D Abeck1, H C Korting, M Kollmann
1Department of Dermatology, University Hospital Eppendorf, Hamburg, Germany.
Abstract:
A collection of 20 strains of Haemophilus ducreyi including freshly isolated, low-passage and multi-passage reference strains was examined for immunoglobulin A1 protease production by SDS-PAGE and immunoblotting. None of the strains demonstrated IgA1 protease activity despite the fact that different culture media were used. By direct immunofluorescence testing, binding of IgA to Haemophilus ducreyi organisms could be demonstrated.