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Published on: February 13, 2021
Computational fluid dynamics-analysis of the Niagara hemodialysis catheter in a right heart model
Guy Mareels1, Dirk S De Wachter, Pascal R Verdonck
1Hydraulics Laboratory, Institute Biomedical Technology, Ghent University, Ghent, Belgium.
Insights
Computational fluid dynamics analysis of the Niagara catheter reveals high wall shear rates, particularly with modified side holes. Reversed connections significantly increase recirculation, highlighting the importance of proper catheter use in dialysis.
Area of Science:
- Biomedical Engineering
- Fluid Dynamics
- Nephrology
Background:
- Central venous catheters are crucial for hemodialysis access.
- Optimizing catheter design is essential for effective and safe dialysis therapy.
Purpose of the Study:
- To analyze the hemodynamic performance of the Niagara central venous catheter using computational fluid dynamics.
- To investigate the impact of side hole modifications and reversed connections on catheter performance.
Main Methods:
- Computational fluid dynamics (CFD) simulations were performed on a Niagara catheter model.
- Simulations included variations in side hole configuration (open, closed, reduced diameter).
- A tube model representing the vena cava and a 3D right atrium model were utilized.
Main Results:
- High wall shear rates exceeding 20,000 s(-1) were observed at the arterial luminal tip.
- Reducing side hole diameter extended the region of elevated shear rates up to 80,000 s(-1).
- Simulated recirculation was negligible with normal connections but reached 30% with reversed connections.
Conclusions:
- The Niagara catheter exhibits significant wall shear rates, influenced by side hole design.
- Proper catheter connection is critical to prevent access recirculation.
- A simplified tube model can effectively predict key hemodynamic properties of central venous catheters.
Abstract:
Central venous catheters are widely used as a hemoaccess method for dialysis therapy. In this study, the performance parameters (velocities, pressure drop, shear rates, access recirculation) of the Niagara catheter are analyzed using computational fluid dynamics. Side holes are left open, closed, or reduced in size to assess the influence of this design feature. Initially the catheter is inserted in a tube which represents the vena cava. In the "arterial" luminal tip, wall shear rates over 20,000 s(-1) are common and peaks attain 55,000 s(-1) at a 300 mL/min blood flow rate. The presence of side holes appears to affect the location but not the level of these elevated shear rates. Halving their diameter causes elevated shear rates to appear in a more extended region with peaks up to 80,000 s(-1). Simulated recirculation percentage is nil in normal catheter use, but attains 30% with reversed catheter connections. The results of the tube model are compared to those of an anatomically realistic right atrium model, which was three-dimensionally reconstructed. It is concluded that most catheter's specific hemodynamic properties can be deduced from the tube model.
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