Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Modulatory effects on human sensorimotor cortex by whole-hand afferent electrical stimulation.

S M Golaszewski1, C M Siedentopf, F Koppelstaetter

  • 1Department of Neurology, University Hospital of Graz, Austria. Stefan.Golaszewski@uibk.ac.at

Neurology
|June 24, 2004
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Altered biodistribution of [<sup>68</sup>Ga]Ga-DOTA-TOC during somatostatin analogue treatment.

European journal of nuclear medicine and molecular imaging·2024
Same author

Will we successfully avoid the garbage in garbage out problem in imaging data mining? An overview on current concepts and future directions in molecular imaging.

Methods (San Diego, Calif.)·2021
Same author

Radiomics for precision medicine: Current challenges, future prospects, and the proposal of a new framework.

Methods (San Diego, Calif.)·2020
Same author

Early thrombosis prophylaxis with enoxaparin is not associated with hematoma expansion in patients with spontaneous intracerebral hemorrhage.

European journal of neurology·2018
Same author

[Lutetium-177-PSMA radioligand therapy : Consensus within the framework of GKV-funded care between the university hospitals in Aachen, Bonn, Düsseldorf, Essen, and Cologne and the MDK Nordrhein].

Der Urologe. Ausg. A·2018
Same author

Correction to: 18F-NaF PET/CT: EANM procedure guidelines for bone imaging.

European journal of nuclear medicine and molecular imaging·2017

Electrical stimulation of hand afferents increased cortical activity in motor and sensory areas. These effects diminished over time, except in the contralateral primary motor cortex, suggesting augmented neuronal excitability.

Area of Science:

  • Neuroscience
  • Human Physiology
  • Motor Control

Background:

  • Understanding cortical plasticity is crucial for rehabilitation.
  • Electrical stimulation is a potential tool for modulating brain activity.

Purpose of the Study:

  • To examine how electrical stimulation of hand nerve afferents influences cortical activity.
  • To assess changes in sensorimotor cortex responses to tactile stimulation after electrical input.

Main Methods:

  • Ten healthy volunteers underwent functional magnetic resonance imaging (fMRI).
  • Participants performed a finger-to-thumb tapping task before and after 30 minutes of sub-sensory electrical stimulation of the left hand.
  • Blood-oxygen-level-dependent (BOLD) responses were analyzed using SPM99.

Related Experiment Videos

Main Results:

  • Electrical stimulation significantly increased movement-related BOLD responses in the primary motor and somatosensory cortex of both hemispheres.
  • These modulatory effects decreased to baseline within two hours post-stimulation.
  • A persistent increase in BOLD response was observed in the contralateral primary motor cortex.

Conclusions:

  • The observed increase in BOLD signal indicates heightened neuronal activity within the sensorimotor cortex.
  • Electrical stimulation of afferents may enhance neuronal excitability in relevant cortical areas.
  • These findings suggest potential therapeutic applications for neuromodulation.