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Recurrent hemiplegia, normal MRI, and NOTCH3 mutation in a 14-year-old: is this early CADASIL?

M R Golomb1, D K Sokol, L E Walsh

  • 1Indiana University School of Medicine, Department of Neurology, Division of Pediatric Neurology, Riley Hospital for Children, Indianapolis, IN 46202, USA.

Neurology
|June 24, 2004
PubMed
Abstract

No abstract available in PubMed .

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The Notch signaling pathway is a major intracellular signaling pathway that is highly conserved over a broad spectrum of metazoan species. It stands unique from other intracellular signaling mechanisms in animals because notch protein itself acts as the receptor as well as the primary signaling molecule.
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