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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
[Detection and morphofunctional predictors of left auricular thrombosis in patients with atrial fibrillation]
I V Zotova1, D A Zateĭshchikov, B A Sidorenko
1Presidential Medical Center of Russia; ul. Marshala Timoschenko, 15, 121356 Moscow, Russia.
Insights
Atrial fibrillation increases stroke risk due to blood clots forming in the heart. Transesophageal echocardiography is key for detecting these clots and guiding anticoagulant therapy in high-risk patients.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Atrial fibrillation (AF) significantly impacts patient quality of life and survival due to thromboembolic complications.
- Intracardiac thrombosis, particularly in the left atrial appendage, is the primary cause of these complications.
- Prevalence of left atrial thrombosis in AF patients ranges from 8% to 24%, with ~90% located in the left auricle.
Purpose of the Study:
- To review methods for detecting left auricular thrombosis.
- To describe structural and functional predictors of thrombosis.
- To discuss modern visualization techniques for these predictors.
Main Methods:
- Review of existing literature on left auricular thrombosis detection.
- Focus on echocardiography, especially transesophageal echocardiography (TEE).
- Assessment of structural and functional predictors using advanced imaging.
Main Results:
- Transesophageal echocardiography is the leading method for assessing thrombosis predictors.
- TEE enables functional monitoring of the left atrium during treatment and post-cardioversion.
- Identification of risk factors is crucial for patient stratification.
Conclusions:
- Early detection of left auricular thrombosis is vital for preventing thromboembolic events.
- Transesophageal echocardiography plays a critical role in diagnosis and monitoring.
- Identifying high-risk patients allows for targeted long-term anticoagulant therapy.
Abstract:
Atrial fibrillation significantly worsens quality and duration of patient's life because of frequent development of thromboembolic complications. The main cause of these complications is formation of intracardiac thrombosis. Prevalence of left atrial thrombosis in patients with atrial fibrillation varies from 8 to 24%. About 90% of thromboses are localized in left auricle. This paper contains review of different methods of detection of left auricular thrombosis. Main structural and functional predictors of thrombosis and possibilities of modern techniques of their visualization are also described. Different methods of echocardiography first of all transesophageal echocardiography are at present foremost in assessment of structural and functional predictors of thrombosis development. With the help of transesophageal echocardiography it is possible to accomplish functional monitoring of the state of left auricle during treatment with different drugs and/or after cardioversion. Detection of risk factors of left auricular thrombosis is an important clinical task because it allows to select a group of high risk patients in which long-term therapy with anticoagulants is indicated.
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