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Published on: June 28, 2019
Complete off-pump coronary revascularization in patients with dialysis-dependent renal disease
Vedat Erentug1, Esat Akinci, Kaan Kirali
1Department of Cardiovascular Surgery, Kosuyolu Heart and Research Hospital, 81020 Istanbul, Turkey. drvedat2002@yahoo.com
Insights
Off-pump coronary artery bypass grafting is a safe and effective treatment for patients with end-stage renal failure and coronary artery disease. This procedure relieved anginal symptoms and showed no perioperative deaths or cardiac events in a small patient group.
Area of Science:
- Cardiovascular Surgery
- Nephrology
- Renal Replacement Therapy
Background:
- Patients with dialysis-dependent renal disease often have coronary artery disease (CAD).
- These patients are considered high-risk surgical candidates for traditional coronary artery bypass grafting (CABG).
Purpose of the Study:
- To evaluate the safety and efficacy of off-pump coronary artery bypass grafting (OPCABG) in dialysis-dependent patients.
- To assess perioperative and early postoperative outcomes, including mortality, morbidity, complications, and transfusion needs.
Main Methods:
- A prospective study of 6 patients with end-stage dialysis-dependent renal failure undergoing complete OPCABG.
- Data collected included perioperative events, postoperative complications, and anginal symptom relief.
Main Results:
- No perioperative deaths or ischemic cardiac events were observed.
- All patients experienced relief from anginal symptoms postoperatively.
- Mean follow-up duration was 172 months.
Conclusions:
- Off-pump coronary revascularization is a viable alternative for patients with end-stage dialysis-dependent chronic renal failure and CAD.
- Thorough preoperative evaluation for risk factors and comorbidities is crucial for this patient population.
Abstract:
Patients who have dialysis-dependent renal disease frequently present with coronary artery disease but are considered at high risk for coronary artery bypass grafting. From 1 September 2000 through 31 August 2003, we performed complete off-pump coronary revascularization in 6 patients who had end-stage dialysis-dependent renal failure, and we prospectively studied the perioperative and early postoperative results. The effect of off-pump coronary artery bypass grafting on mortality, morbidity, postoperative complications, and transfusion requirements in this group of patients was investigated. No perioperative deaths or ischemic cardiac events were observed after off-pump coronary artery bypass grafting. In all patients, anginal symptoms were relieved during the postoperative period. The mean duration of follow-up was 172 +/- 12.4 months. Patients with dialysis-dependent chronic renal failure who present with coronary artery disease should be thoroughly evaluated preoperatively for risk factors and coexistent severe diseases. We believe that in patients with end-stage dialysis-dependent chronic renal failure, off-pump coronary revascularization is a good alternative.
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