Related Experiment Videos
Trisomy 4 in a case of acute lymphocytic leukemia (L1)
K Hodohara1, Y Fujiyama, T Inoue
1Second Department of Internal Medicine, Shiga University of Medical Science, Otsu, Japan.
Cancer Genetics and Cytogenetics
|August 1, 1992
Abstract:
Trisomy 4 has been identified previously as a chromosome abnormality associated with acute nonlymphocytic leukemia (ANLL) with myelomonocytic lineage and in myelodysplastic syndromes (MDS). We report a case of acute lymphocytic leukemia (ALL) (French-American-British, FAB L1) in a 42-year-old Japanese man, with trisomy 4 as the sole chromosomal anomaly. Immunophenotypically, the leukemic blasts demonstrated reactivity with CD2, CD5, and CD7 and indicated on early stage of T cell.