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Postmenopausal bleeding resulting from placental site trophoblastic tumor of the uterus: a case report
Masoumeh Fallahian1, Bahar Jafari
1Departments of Obstetrics and Gynecology, Shaheed Beheshti Medical Science University, Taleghani Hospital, Tehran, Iran.
Background:
Placental site trophoblastic tumor (PSTT) is the least common form of gestational trophoblastic disease. Occurrence of PSTT after menopause is extremely rare.
Case:
A 53-year-old woman complained of postmenopausal bleeding 6 years after cessation of her menstrual periods. On dilatation and curettage and on hysterectomy and bilateral salpingo-oophorectomy later, PSTT was found in the uterus with myometrial invasion and no metastasis. Serum human chorionic gonadotropin levels before and after the operation were 15 and < 1 IU/mL, respectively. Hysterectomy was performed.
Conclusion:
Because of PSTT's rarity, limited information is known about its natural history, and there is no reliable means to predict clinical outcome. Thus, patients must be evaluated on a case-by-case basis.