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Updated: Aug 2, 2026

Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
Published on: December 11, 2016
Effects of sandfly fever on isometric muscular strength, endurance, and recovery
E A Alluisi1, W R Beisel, L S Caldwell
1Air Force Human Resources Laboratory, Brooks Air Force Base, Texas 78235, USA.
Abstract:
The isometric muscular strength and endurance of 10 male volunteers were measured four times per day for 15 consecutive days. Eight experimental subjects were inoculated with sandfly fever virus and two double-blind controls were given sterile saline on the seventh day. The muscular performances of the control subjects remained essentially constant throughout. Decrements in muscular strength and endurance occurred with the experimentals during the brief period of illness three or four days after inoculation, then performances improved towards baseline levels.
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