Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The embryo and its future.

Tom P Fleming1, Wing Yee Kwong, Richard Porter

  • 1School of Biological Sciences, University of Southampton, Southampton SO16 7PX, United Kingdom. tpf@soton.ac.uk

Biology of Reproduction
|June 25, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Applying cultural psychiatry to non-pharmacological interventions.

BJPsych open·2026
Same author

Cardiometabolic screening, elevated results and clinical follow-up actions in Ma-ori and non-Ma-ori with psychosis in Canterbury, Aotearoa New Zealand.

The Australian and New Zealand journal of psychiatry·2026
Same author

Shifting the Overton Window: enhancing therapeutic outcomes for Māori experiencing Ngā Māuiui kai (eating disorders) through the integration of traditional Māori and Western healing systems in Aotearoa New Zealand.

Frontiers in psychiatry·2026
Same author

Lithium: challenges of being king.

The British journal of psychiatry : the journal of mental science·2026
Same author

Sex-specific multigenerational epigenetic responses to real-world chemical mixture exposure in an outbred sheep model.

bioRxiv : the preprint server for biology·2026
Same author

Intraoperative neurophysiological monitoring changes during surgical correction of pediatric neuromuscular scoliosis: a single-institution report.

Spine deformity·2026

Early mammalian embryo development is sensitive to environmental factors, impacting long-term health and phenotype. Understanding these influences is crucial for clinical health and biotechnology.

Area of Science:

  • Developmental biology
  • Epigenetics
  • Reproductive medicine

Background:

  • Preimplantation mammalian embryos are sensitive to their environment (in vitro/in vivo).
  • Environmental factors like culture conditions and maternal diet can cause lasting changes.
  • These changes affect fetal and postnatal growth, phenotype, and overall health.

Purpose of the Study:

  • To review environmental influences on early embryo development.
  • To explore embryo responses across epigenetic, metabolic, cellular, and physiological levels.
  • To evaluate how these responses impact later gestation, developmental potential, and phenotype.

Main Methods:

  • Literature review of environmental impacts on preimplantation embryos.
  • Analysis of epigenetic, metabolic, cellular, and physiological responses.

Related Experiment Videos

  • Evaluation of links between early environment and later developmental outcomes.

    • Main Results:

    • Environmental sensitivity is a key feature of early mammalian embryos.
    • Diverse environmental factors can induce long-term alterations in growth and phenotype.
    • Embryo responses to the environment have significant implications for future health.

    Conclusions:

    • A complex interplay of mechanisms connects the early embryo's environment to future health.
    • Understanding these mechanisms is vital for clinical applications and reproductive technologies.
    • Early life environmental exposures can program long-term health trajectories.