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Coronary Angiography During Ex-Situ Heart Perfusion in a Porcine Model
Published on: July 12, 2024
Coronary dilators and cardioplegia
Alexander Romagnoli1, Adolph J. Koska
1Cardiovascular Anesthesia Division, Texas Heart Institute, Houston, Texas.
Abstract:
The distribution in the myocardium of cardioplegic solution is demonstrated in dog hearts with the aid of indocyanine green. When papaverine or nitroglycerin are added to the solution, a much improved diffusion is observed. Papaverine appears to be a better coronary dilator. We deduce from this observation that myocardial protection during ischemic arrest for open-heart surgery is enhanced considerably when coronary dilation is assured.
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