A stereodivergent asymmetric approach to difluorinated aldonic acids
Christophe Audouard1, Igor Barsukov, John Fawcett
1Department of Chemistry, University of Leicester, University Road, Leicester, UK LE1 7RH.
Chemical Communications (Cambridge, England)
|June 25, 2004
Abstract:
A (bromodifluoromethyl)alkyne has been deployed in a stereoselective route to difluorinated aldonic acid analogues, in which a Sharpless asymmetric dihydroxylation reaction and diastereoisomer separation set the stage for phenyl group oxidation.
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