Related Experiment Video
Updated: Aug 23, 2026

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium
Published on: May 31, 2024
Absenteeism among employees with irritable bowel syndrome
Christopher Zacker1, Anita J Chawla, Shaohung Wang
1Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA. christopher.zacker@pharma.novartis.com
Abstract:
Patterns of illness or disability-related work absence six months before and six months after a diagnosis of irritable bowel syndrome (IBS) were assessed from medical claims and absenteeism databases and were compared with a sample of patients with no gastrointestinal (GI) disorders. The records of 630 patients with IBS were compared with those of 1,260 persons without GI conditions. Mean monthly IBS-related absences increased by 69% (from 0.96 to 1.62 days) from the beginning of the six-month period before diagnosis to the month of diagnosis. With multivariate regression analysis, the incremental effect of an IBS diagnosis on six-month absenteeism was estimated to be 3.27 absences greater for persons with IBS.
More Related Videos
Related Concept Videos
Irritable Bowel Syndrome III: Medical and Nursing Management
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome I: Introduction
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...

