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Updated: Aug 23, 2026

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
Published on: January 26, 2016
Three cyclooctapeptides and one glycoside from Microtoena prainiana
Chong-Qian Li1, Bo-Gang Li, Hua-Yi Qi
1West China School of Pharmacy, Sichuan University, Chengdu 610041, People's Republic of China.
Abstract:
Three new cyclic octapeptides, microtoenins A-C (1-3), and a new glycoside, 3'''-O-methylcrenatoside (4), along with several known compounds, were isolated from the ethanolic extract of the stems of Microtoena prainiana. Their structures were determined by spectral and chemical evidence. At a concentration of 0.01 mg/mL, 3'''-O-methylcrenatoside (4), crenatoside (5), and isocrenatoside (6) inhibited angiotensin converting enzyme (ACE) activity by more than 30%.
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