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[Thyroid function tests in healthy and ill elderly].

A L Cervantes Covarrubias1, J Halabe Cherem, H Nellen Hummel

  • 1Departamento de Medicina Interna del Hospital de Especialidades, Centro Médico Nacional Siglo XXI, IMSS.

Gaceta Medica De Mexico
|January 1, 1992
PubMed
Summary
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Thyroid function tests (T3, T4, T4L, TSH) revealed significant alterations in hospitalized elderly patients compared to ambulatory controls. Hospitalized elderly individuals exhibited notably lower triiodothyronine (T3) levels, indicating thyroid dysfunction in this population.

Area of Science:

  • Gerontology
  • Endocrinology
  • Clinical Medicine

Background:

  • Thyroid function in the elderly is complex and debated.
  • Age-related physiological changes can impact thyroid hormone levels.
  • Distinguishing normal aging from disease-related thyroid dysfunction is crucial.

Purpose of the Study:

  • To compare thyroid function tests between hospitalized and ambulatory elderly individuals.
  • To investigate potential differences in thyroid hormone levels based on sex and age within elderly cohorts.
  • To identify alterations in thyroid function associated with hospitalization in older adults.

Main Methods:

  • Cross-sectional study comparing two groups of elderly individuals (n=72 each).
  • Group I: Hospitalized patients (average age 72.97 years).

Related Experiment Videos

  • Group II: Ambulatory asymptomatic elderly (average age 69.81 years).
  • Measurement of serum triiodothyronine (T3), thyroxine (T4), free thyroxine index (T4L), and thyroid-stimulating hormone (TSH).

    • Main Results:

    • Hospitalized patients (Group I) showed significantly lower mean T3 levels compared to ambulatory controls (Group II).
    • Significant differences in T3 and T4 levels were observed in males of Group I.
    • Lower T4L levels were noted in women of Group II and in specific age subgroups (70-89 years) of Group II.
    • A higher proportion of thyroid function test alterations were found in hospitalized elderly patients.

    Conclusions:

    • Thyroid function tests tend to be normal in asymptomatic ambulatory elderly individuals.
    • Hospitalized elderly patients demonstrate a significant prevalence of thyroid function abnormalities.
    • These findings highlight the importance of assessing thyroid status in elderly patients, particularly those who are hospitalized.