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Optical fiber-based biosensors.

David J Monk¹, David R Walt

¹Department of Chemistry, Pearson Lab, Tufts University, 62 Talbot Ave., Medford, MA 02155, USA. david.monk@tufts.edu

Analytical and Bioanalytical Chemistry

|June 29, 2004

Summary

This summary is machine-generated.

This review covers optical fiber biosensor research from 2001-2003, detailing their classification by biological recognition elements like enzymes and antibodies for detecting various analytes.

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Area of Science:

Biomedical Engineering
Analytical Chemistry
Optoelectronics

Background:

Optical fiber biosensors integrate biological recognition elements with optical fibers.
This review complements prior work, focusing on research from January 2001 to September 2003.
These sensors offer versatile applications in detecting a wide range of substances.

Purpose of the Study:

To provide a comprehensive overview of optical fiber-based biosensor research during a specific period.
To classify existing biosensor designs based on their biological recognition components.
To highlight the potential of these sensors for diverse analytical applications.

Main Methods:

Literature review of scientific publications from January 2001 to September 2003.
Classification of biosensors based on recognition element: enzyme, antibody/antigen (immunoassay), nucleic acid, whole cell, and biomimetic.
Analysis of sensor applications for various analytes including metals, chemicals, and physiological materials.

Main Results:

Identified key advancements and trends in optical fiber biosensor technology within the review period.
Detailed the classification of biosensors according to their biological recognition elements.
Demonstrated the broad applicability of these sensors for detecting diverse analytes.

Conclusions:

Optical fiber biosensors represent a significant area of research with diverse applications.
The classification based on recognition elements provides a useful framework for understanding sensor types.
Continued development in this field promises further advancements in analytical sensing capabilities.