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Bilateral pheochromocytoma during pregnancy
Vorapong Phupong1, Pairoj Witoonpanich, Thiti Snabboon
1Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand. vorapong.p@chula.ac.th
Archives of Gynecology and Obstetrics
|June 29, 2004
Summary
Bilateral pheochromocytoma in pregnancy is rare but manageable. Early diagnosis and surgical removal of catecholamine-secreting tumors lead to favorable outcomes for both mother and child.
Area of Science:
- Endocrinology
- Obstetrics
- Surgical Oncology
Background:
- Pheochromocytoma, a rare tumor of chromaffin cells, can occur during pregnancy.
- Bilateral pheochromocytoma presents an even rarer clinical scenario.
- Hypertension in pregnancy necessitates a broad differential diagnosis.
Observation:
- A 26-year-old pregnant patient presented with severe hypertension and headache.
- Investigation revealed bilateral pheochromocytoma.
- The patient underwent bilateral adrenalectomy at 23 weeks' gestation and Cesarean section at 31 weeks due to intrauterine growth retardation.
Findings:
- Successful surgical management of bilateral pheochromocytoma during pregnancy.
- Uneventful maternal outcome post-adrenalectomy and Cesarean section.
- Neonatal complications were limited to jaundice.
Implications:
- Pheochromocytoma should be considered in the differential diagnosis of hypertension during pregnancy.
- Timely diagnosis and multidisciplinary management improve maternal and fetal prognosis.
- Surgical intervention for pheochromocytoma in pregnancy can achieve positive outcomes.