Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Breast carcinoma in men: a population-based study.

Sharon H Giordano1, Deborah S Cohen, Aman U Buzdar

  • 1Department of Breast Medical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, PO Box 424, Houston, TX 77030, USA. sgiordan@mdanderson.org

Cancer
|June 29, 2004
PubMed
Summary

The incidence of male breast carcinoma is rising, with men diagnosed at older ages and more advanced stages. Survival rates are similar between sexes when adjusted for disease stage.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular Characterization and Prospective Evaluation of Pathologic Response and Outcomes with Neoadjuvant Therapy in Metaplastic Triple-Negative Breast Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research·2022
Same author

Thinking About Pathomechanisms and Current Treatment of Erectile Dysfunction-"The Stanley Beamish Problem." Review, Recommendations, and Proposals.

Sexual medicine reviews·2020
Same author

Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action.

JCI insight·2020
Same author

Single-nucleotide polymorphism biomarkers of adjuvant anastrozole-induced estrogen suppression in early breast cancer.

Pharmacogenetics and genomics·2020
Same author

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2.

Clinical pharmacology and therapeutics·2019
Same author

Disease-Free and Overall Survival Among Patients With Operable HER2-Positive Breast Cancer Treated With Sequential vs Concurrent Chemotherapy: The ACOSOG Z1041 (Alliance) Randomized Clinical Trial.

JAMA oncology·2018

Area of Science:

  • Oncology
  • Epidemiology
  • Cancer Research

Background:

  • Male breast carcinoma is rare, with limited data from small studies.
  • Previous research has not fully elucidated incidence, characteristics, or survival.
  • Understanding male breast cancer is crucial for comparative analysis with female breast cancer.

Purpose of the Study:

  • To determine the incidence and trends of male breast carcinoma.
  • To compare clinical and demographic characteristics between male and female breast cancer patients.
  • To identify prognostic factors and survival rates for male breast carcinoma.

Main Methods:

  • Utilized the National Cancer Institute Surveillance, Epidemiology, and End Results database (1973-1998).
  • Calculated age-adjusted incidence rates and compared patient/tumor characteristics.

Related Experiment Videos

  • Performed univariate and multivariate analyses to assess survival predictors.

    • Main Results:

    • Incidence of male breast carcinoma increased significantly (0.86 to 1.08 per 100,000).
    • Men were diagnosed at older ages, with more lymph node involvement, advanced stage, and hormone receptor-positive tumors.
    • Larger tumor size and lymph node involvement were linked to poorer survival in men.

    Conclusions:

    • Male breast carcinoma incidence is increasing, though it remains uncommon.
    • Epidemiologic and biologic differences exist between male and female breast cancers.
    • Survival rates by stage are comparable between men and women.