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Updated: Aug 23, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
[Prognosis of periprosthetic regurgitation after mitral valve replacement using the Saint Jude prosthesis]
A Mahdhaoui1, M A Majdoub, H Bouraoui
1Service de cardiologie, CHU Farhat-Hached, 4000 Sousse, Tunisie. abdallah.mahdhaoui@famso.rnu.tn
Unlabelled:
Periprosthetic regurgitation (PPR) is a common complication of mitral valve replacement (MVR). The management of moderate and minor PPR remains controversial. The goal of this prospective study was to determine the incidence, predictors and outcome of PPR discovered using omniplan transoesophageal echocardiography (TEE) performed at the early postoperative period (14.7 days) of MVR with SJM prosthesis. Our study enrolled 56 patients, the mean age was 44.5 +/- 11.9 years. The incidence of PPR was 59% (33 patients). TEE showed one jet in nine patients (27%), two jets in 23 patients (70%) and three jets in one patient (3%). PPR is minor in 24 patients (63%) and moderate in nine patients (27%). No patient developed hemolytic anemia or congestive heart failure. In univariate analysis, diameter of prostheses > 27 mm, number of suture knots < 17 and diameter of prostheses/number of knot ratio > 1.7 independently predicted the presence of PPR. In multivariate analysis only a rapport diameter of protheses/number of suture knots > 1.7 mm is predictif of PPR (odd ratio = 9, P = 0.036). Ninety percent of PPR remained present at six weeks and only 29% were present after 12.5 months.
Conclusion:
Mild and minor PPR were frequent during the early postoperative period after MVR. The clinical significance and natural history is benign and they do not require any specific treatment.
Insights
Mild periprosthetic regurgitation (PPR) after mitral valve replacement (MVR) is common and typically benign. This early postoperative complication, often detected by transesophageal echocardiography (TEE), usually resolves or remains clinically insignificant without specific treatment.
Area of Science:
- Cardiovascular Surgery
- Echocardiography
- Prosthetic Valve Complications
Background:
- Periprosthetic regurgitation (PPR) is a recognized complication following mitral valve replacement (MVR).
- The management of mild and moderate PPR after MVR is not well-defined.
- Early identification and characterization of PPR are crucial for patient outcomes.
Purpose of the Study:
- To investigate the incidence, predictors, and natural history of PPR after MVR using St. Jude Medical (SJM) prostheses.
- To evaluate the role of omniplane transesophageal echocardiography (TEE) in detecting early postoperative PPR.
- To determine the clinical significance of mild and moderate PPR.
Main Methods:
- Prospective study involving 56 patients undergoing MVR with SJM prostheses.
- Early postoperative transesophageal echocardiography (TEE) was performed on average 14.7 days after surgery.
- Analysis included incidence, jet characteristics, severity grading, and follow-up assessments at 6 weeks and 12.5 months.
Main Results:
- The incidence of PPR was 59%, with most cases being minor (63%) or moderate (27%).
- A prosthesis diameter/suture knot ratio greater than 1.7 was a significant predictor of PPR (OR=9, P=0.036).
- PPR persisted in 90% at 6 weeks and 29% at 12.5 months, with no associated hemolytic anemia or heart failure.
Conclusions:
- Mild and minor PPR are frequent early after MVR.
- The clinical significance and natural history of these PPR cases appear benign.
- No specific treatment is typically required for mild or minor PPR detected early post-MVR.
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