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Updated: Aug 15, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
A mathematical model for the burden of diabetes and its complications
A Boutayeb1, E H Twizell, K Achouayb
1Department of mathematics and statistics, Brunel University, Uxbridge middx UB8 3PH, UK. masraab@brunel.ac.uk
Background:
The incidence and prevalence of diabetes are increasing all over the world. Complications of diabetes constitute a burden for the individuals and the whole society.
Methods:
In the present paper, ordinary differential equations and numerical approximations are used to monitor the size of populations of diabetes with and without complications.
Results:
Different scenarios are discussed according to a set of parameters and the dynamical evolution of the population from the stage of diabetes to the stage of diabetes with complications is clearly illustrated.
Conclusions:
The model shows how efficient and cost-effective strategies can be obtained by acting on diabetes incidence and/or controlling the evolution to the stage of complications.
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