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Development, structure and function of the upper airways.

Petr Pohunek1

  • 12nd Paediatric Department, Division of Paediatric Pulmonology, University Hospital Motol, V Uvalu 84, 150 06 Praha 5, Czech Republic. petr.pohunek@lfmotol.cuni.cz

Paediatric Respiratory Reviews
|June 30, 2004
PubMed
Summary

Understanding upper airway development is crucial for comprehending their function. Key developmental events occur during embryonic and postnatal growth, influencing air conduction and protection.

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Area of Science:

  • Anatomy and Physiology
  • Developmental Biology

Background:

  • The upper airways are vital for respiration, air conditioning, olfaction, phonation, and lower airway protection.
  • Their structure and mucosal properties significantly impact inhaled air quality.

Purpose of the Study:

  • To elucidate the critical developmental events of the upper airways.
  • To emphasize the importance of understanding both prenatal and postnatal development for functional insights.

Main Methods:

  • Review of key developmental milestones in embryogenesis.
  • Analysis of postnatal airway growth patterns relative to skeletal development.

Main Results:

  • Major upper airway development occurs during early embryonic stages.

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  • Postnatal growth parallels head, neck, and thoracic skeletal growth, with accelerated growth in the first two years.

    • Conclusions:

    • A comprehensive understanding of upper airway function necessitates a thorough knowledge of their prenatal and postnatal developmental trajectory.
    • Developmental insights are key to appreciating the complex roles of the upper airways.