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Updated: Aug 23, 2026

Generation and Multi-phenotypic High-content Screening of Coxiella burnetii Transposon Mutants
Published on: May 13, 2015
Constrictive pericarditis due to Coxiella burnetii
Víctor Bautista-Hernández1, Francisco Gutierrez, Víctor G Ray
1Regional Service of Cardiovascular Surgery, University Hospital Virgen de la Arrixaca, Murcia, Spain. vbautista-hernandez@hotmail.com
Abstract:
Q fever is characterized by its clinical polymorphism. Cardiac involvement in acute Q fever is rare. We report a case of pleuro-pericarditis that rapidly evolved to pericardial constriction during an acute episode of Coxiella burnetii infection. Constrictive pericarditis was confirmed by hemodynamic measurements, echocardiography, and magnetic resonance. Indirect immunofluorescence assay revealed positive serology for acute Q fever. The patient underwent a successful pericardiectomy and was given antibiotics. The histopathologic study of the excised pericardium showed C. burnetii in a large cluster of organisms. After a 6-month follow-up period, the individual was asymptomatic.
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