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Updated: Aug 23, 2026

Fate Mapping of Human Embryonic Stem Cells by Teratoma Formation
Published on: August 1, 2010
Immature intrapericardial teratoma in a newborn with elevated alpha-fetoprotein
Nathalie Roy1, Dominic J Blurton, Anthony Azakie
1Division of Pediatric Cardiothoracic Surgery, Children's Hospital, University of California, San Francisco, San Francisco, California 94143-0118, USA.
Abstract:
A large intrapericardial mass was incidentally found in a fetus at 32 weeks gestational age, which was accompanied by a significant pericardial effusion. The baby was delivered by cesarean section and had surgical removal of the tumor on the second day of life. Alpha-fetoprotein was elevated. The pathologic analysis demonstrated a grade I immature teratoma with foci of hepatoid tissue. The patient had an uneventful postoperative recovery. A review of the literature and pathologic implications are discussed.

