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Published on: May 21, 2017
Different characteristics of postoperative heart failure after surgery for aortic stenosis and coronary disease
Farkas Vánky1, Erik Håkanson, Tamás Maros
1Department of Cardiothoracic Surgery, Linköping Heart Center, University Hospital, Linköping, Sweden.
Insights
Postoperative heart failure (PHF) incidence was similar after aortic valve replacement (AVR) and coronary artery bypass grafting (CABG). However, PHF characteristics and one-year survival differed significantly between the two surgical groups.
Area of Science:
- Cardiology
- Cardiac Surgery
- Heart Failure Research
Background:
- Postoperative heart failure (PHF) is a critical factor influencing outcomes in cardiac surgery patients.
- Limited research exists on the distinct characteristics of PHF following valve surgery versus coronary artery bypass grafting (CABG).
Purpose of the Study:
- To investigate and compare the specific features of PHF in patients undergoing isolated aortic valve replacement (AVR) versus on-pump isolated CABG.
- To identify potential differences in the causes and clinical presentation of PHF between these two major cardiac surgical procedures.
Main Methods:
- A comparative study involving 398 patients undergoing isolated AVR for aortic stenosis and 398 age- and sex-matched patients undergoing isolated on-pump CABG.
- Detailed analysis of 45 AVR patients and 47 CABG patients who required treatment for PHF.
Main Results:
- The AVR group experienced longer aortic cross-clamp times and a higher incidence of isolated right ventricular failure.
- Myocardial ischemia during induction and perioperative myocardial infarction were more prevalent in the CABG group.
- One-year mortality was notably higher in the CABG group (25.5%) compared to the AVR group (8.9%).
Conclusions:
- While the incidence of PHF was comparable between AVR and CABG, distinct clinical characteristics were observed.
- Isolated right ventricular failure and PHF secondary to septicemia were more frequent in AVR patients.
- PHF in CABG patients was more strongly linked to myocardial ischemia and infarction, potentially explaining the poorer survival rates in this cohort.
Objective:
Postoperative heart failure (PHF) remains a major determinant of outcome after cardiac surgery. However, possible differences in characteristics of PHF after valve surgery and coronary surgery (CABG) have received little attention. Therefore, this issue was studied in patients undergoing aortic valve replacement (AVR) and CABG, respectively.
Design:
Three hundred and ninety-eight patients undergoing isolated AVR for aortic stenosis were compared with 398 patients, matched for age and sex, undergoing on-pump isolated CABG. Forty-five AVR and 47 CABG patients required treatment for PHF and these were studied in detail.
Results:
The AVR group had longer aortic cross-clamp time and higher rate of isolated right ventricular heart failure postoperatively. Myocardial ischemia during induction and perioperative myocardial infarction were more common in the CABG group. One-year mortality was 8.9% in the AVR group vs 25.5% in the CABG group (p = 0.05).
Conclusions:
The incidence of PHF was similar in both groups but different characteristics were found. Isolated right ventricular failure and PHF precipitated by septicemia were more common in AVR patients. PHF was more clearly associated with myocardial ischemia and infarction in CABG patients, which could explain their less favorable survival.
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