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Cigarette smoking and diabetes mellitus
F Beziaud1, J M Halimi, P Lecomte
1Service de Médecine interne B, CHU Tours, France.
Diabetes & Metabolism
|June 30, 2004
Summary
Cigarette smoking increases type 2 diabetes risk in men but not significantly in women. Smoking cessation did not reduce diabetes risk in this French population study.
Area of Science:
- Epidemiology
- Public Health
- Endocrinology
Background:
- Cigarette smoking is a global health concern with known links to various diseases.
- The specific relationship between smoking and type 2 diabetes, particularly its differential impact on men and women, requires further investigation.
Purpose of the Study:
- To determine if an independent association exists between cigarette smoking and type 2 diabetes in a French population.
- To evaluate the influence of active smoking and smoking cessation on diabetes prevalence.
Main Methods:
- A population-based cross-sectional study involving 28,409 volunteers.
- Statistical analysis adjusted for age, body mass index (BMI), waist-hip ratio (WHR), and alcohol consumption.
Main Results:
- Men who currently smoke or are former smokers have a significantly higher risk of type 2 diabetes (OR 1.49 and 1.31, respectively).
- Women smokers showed a less significant association with diabetes risk (HR 1.46), with no significant link found for former smoking.
- Adjusted fasting glucose levels were higher in male smokers and former smokers, but lower in female current smokers compared to non-smokers.
Conclusions:
- Smoking is linked to increased type 2 diabetes risk primarily in men, with a weaker association in women.
- The impact of smoking on fasting glucose levels differs between genders.
- Smoking cessation did not demonstrate a reduced risk of developing diabetes in this study population.