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Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
NICE guidelines for chronic obstructive pulmonary disease--a review
1Portsmouth Hospitals NHS Trust.
Abstract:
In the UK the prevalence of chronic obstructive pulmonary disease has been estimated at one per cent, rising to five per cent of men aged 65-74 years and 10 per cent of men aged over 75 years. It is thought that only a quarter of COPD cases are diagnosed (Calverley and Bellamy, 2000). The symptoms of breathlessness, chronic cough, and regular sputum production usually develop insidiously. However, COPD not only affects the lungs but has extra pulmonary effects such as muscle wasting and weight loss, pulmonary hypertension, cor pulmonale (enlargement of the right side of the heart), anxiety, and depression.
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