Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Auditory function recovery following acoustic overstimulation.

J M Sánchez Fernández1, A Martínez Ibargüen, N Avalos Cuica

  • 1Otorhinolaryngology Department, Basurto Hospital, School of Medicine, Basque Country University, Bilbao, Spain. rozalvem@lg.ehu.es

Acta Oto-Laryngologica
|July 1, 2004
PubMed
Summary

Auditory brainstem responses (ABRs) and distortion product otoacoustic emissions (DPOAEs) in chickens showed significant amplitude loss after noise exposure. DPOAEs recovered in 5 days, while ABRs normalized in 15 days.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preliminary study of the lymphatic drainage system of the nose and paranasal sinuses and its role in detection of sentinel metastatic nodes.

Acta oto-laryngologica·2005
Same author

Distortion-product otoacoustic emissions study of the noise-induced toughening effect in rats.

Acta oto-laryngologica·2003
Same author

[Comparative study of the use of manual and mechanical suturing in the closure of the mucosal defect in total laryngectomy].

Acta otorrinolaringologica espanola·2002
Same author

Morphometric study of the paranasal sinuses in normal and pathological conditions.

Acta oto-laryngologica·2001
Same author

[Middle ear physiology].

Revue de laryngologie - otologie - rhinologie·2000
Same author

[Intramuscular epithelioid hemangioma of the parapharyngeal space].

Acta otorrinolaringologica espanola·1999

Area of Science:

  • Auditory neuroscience
  • Ototoxicity research
  • Animal models in hearing science

Background:

  • Acoustic overstimulation can cause temporary or permanent hearing damage.
  • Electrophysiological measures like ABRs and DPOAEs are crucial for assessing auditory function and damage.
  • Chickens serve as a valuable model for studying auditory system development and response to injury.

Purpose of the Study:

  • To investigate the impact of acoustic overstimulation on auditory function in chickens.
  • To compare the recovery patterns of auditory brainstem responses (ABRs) and distortion product otoacoustic emissions (DPOAEs) after noise exposure.

Main Methods:

  • 15 white Leghorn chickens (15 days old) were exposed to a 2-kHz pure tone at 120 dB SPL for 24 hours.
  • Auditory brainstem responses (ABRs) and distortion product otoacoustic emissions (DPOAEs) were recorded before and at multiple time points after acoustic exposure.

Related Experiment Videos

  • Electrophysiological data were collected using specialized equipment for ABR and DPOAE analysis.

    • Main Results:

    • Acoustic overstimulation caused significant amplitude loss across all tested frequencies in both DPOAEs and ABRs immediately post-exposure.
    • DPOAE amplitude loss was largely recovered by 5 days post-exposure, with only a minor residual effect at 3 kHz.
    • Auditory brainstem response (ABR) thresholds showed a significant shift immediately after exposure, with complete recovery observed by 15 days post-exposure.

    Conclusions:

    • Distortion product otoacoustic emissions demonstrated a faster recovery from acoustic overstimulation compared to auditory brainstem responses in chickens.
    • The findings highlight differential recovery timelines for outer hair cell function (DPOAEs) and neural pathway integrity (ABRs) following noise-induced hearing loss.