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Updated: Aug 23, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Ovarian stimulation for in vitro fertilization in patients with endometriosis
Kostantinos Zikopoulos1, Efstratios M Kolibianakis, Paul Devroey
1Center for Reproductive Medicine, Dutch-Speaking Brussels Free University, Brussels, Belgium.
Abstract:
The use of gonadotropin-releasing hormone (GnRH) agonists in a long protocol appears to enhance the probability of conception in the presence of endometriosis. In addition, there is evidence to suggest that the use of prolonged downregulation with GnRH agonists prior to ovarian stimulation for in vitro fertilization (IVF) is beneficial for achieving pregnancy. Until now, GnRH antagonists have not been used in patients with endometriosis. The management of endometriomas prior to stimulation for IVF and its impact on reproductive outcome are still subject to debate.
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