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Immunonutrition and cancer.

Martin Philpott1, Lynnette R Ferguson

  • 1Discipline of Nutrition and ACSRC, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand. m.philpott@auckland.ac.nz

Mutation Research
|July 1, 2004
PubMed
Summary
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Chronic inflammation increases cancer risk. Certain nutrients like zinc, EGCG, omega-3s, and probiotics can modulate immune responses and potentially prevent cancer. Immunonutrition offers a less invasive approach.

Area of Science:

  • Immunology
  • Oncology
  • Nutrition Science

Background:

  • The immune system defends against pathogens and cancer cells.
  • Inflammatory processes are crucial but excessive or chronic inflammation increases cancer risk.
  • Chronic inflammation can be triggered by various factors including chemicals, pathogens, and disease processes.

Purpose of the Study:

  • To explore the role of specific nutrients in modulating immune responses and counteracting inflammation.
  • To investigate the potential of immunonutrition in preventing cancer development and progression associated with chronic inflammation.

Main Methods:

  • Review of scientific literature on the immunomodulatory and anti-inflammatory effects of key nutrients.
  • Analysis of the mechanisms by which nutrients like zinc, epigallocatechin galate (EGCG), omega-3 polyunsaturated fatty acids, and probiotics influence immune responses.

Related Experiment Videos

  • Evaluation of the potential of these nutrients in the context of cancer prevention and progression.

    • Main Results:

    • Several nutrients, including zinc, EGCG, omega-3 fatty acids, and probiotics, demonstrate the ability to modulate immune responses.
    • These nutrients exhibit potential in protecting against cancer development and progression.
    • Different nutrients employ distinct mechanisms to achieve immunomodulation and anti-inflammatory effects.

    Conclusions:

    • Immunonutrition, utilizing specific dietary components, shows promise in managing chronic inflammation-related cancers.
    • Nutrients can modulate immune responses, offering a potential strategy for cancer prevention.
    • Immunonutrition may serve as a less invasive alternative to immunotherapy for cancers linked to chronic inflammation.