Related Experiment Video

Updated: Aug 23, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

Congenitally corrected transposition in a patient with situs inversus, atrioventricular discordance and mesocardia

J S de Lezo1, J Herreros, M Côté

  • 1Cardiology Service, Department of Medicine, Centre Hospitalier Universitaire, Sherbrooke, Province of Québec, Canada.

Texas Heart Institute Journal
|September 1, 1983
PubMed

Insights

This study presents a rare case of corrected transposition of great arteries in situs inversus, detailing its clinical and hemodynamic features. It compares associated anomalies and surgical considerations with situs solitus cases.

Area of Science:

  • Cardiology
  • Congenital Heart Disease
  • Medical Case Reports

Background:

  • Situs inversus is a rare condition where major visceral organs are reversed.
  • Corrected transposition of the great arteries (cTGA) is a complex congenital heart defect.
  • The co-occurrence of situs inversus and cTGA presents unique clinical challenges.

Purpose of the Study:

  • To present the clinical, hemodynamic, and angiographic features of a patient with situs inversus, atrioventricular discordance, cTGA (I,D,D), and mesocardia.
  • To review the literature on cTGA in situs inversus.
  • To compare associated anomalies and discuss surgical aspects.

Main Methods:

  • Case presentation of a patient with complex congenital heart disease.
  • Literature review of corrected transposition of the great arteries in situs inversus.
  • Comparative analysis of cardiovascular and electrocardiographic anomalies.

Main Results:

  • Detailed clinical, hemodynamic, and angiographic findings for the presented case.
  • Incidence of associated anomalies in situs inversus cTGA compared to situs solitus cTGA.
  • Discussion of specific surgical considerations for this rare condition.

Conclusions:

  • The combination of situs inversus and cTGA is exceptionally rare.
  • Understanding associated anomalies is crucial for patient management.
  • Specialized surgical approaches may be required for these complex cases.

More Related Videos

Implantation of Total Artificial Heart in Congenital Heart Disease07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Development of the Heart01:27

Development of the Heart

The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
Meiosis I01:49

Meiosis I

Meiosis is a carefully orchestrated set of cell divisions, the goal of which—in humans—is to produce haploid sperm or eggs, each containing half the number of chromosomes present in somatic cells elsewhere in the body. Meiosis I is the first such division, and involves several key steps, among them: condensation of replicated chromosomes in diploid cells; the pairing of homologous chromosomes and their exchange of information; and finally, the separation of homologous chromosomes by a...