Coarctation of the aorta in infancy
M J Levy1, L Levinsky, E Deviri
1Thoracic and Cardiovascular Surgery Department, Beilinson Medical Center, Tel Aviv University Medical School, Tel Aviv, Israel.
Insights
Surgical repair of coarctation of the aorta in infants showed a high survival rate. Most deaths and late complications in survivors were linked to associated intracardiac anomalies.
Area of Science:
- Cardiology
- Pediatric Surgery
- Congenital Heart Disease
Background:
- Coarctation of the aorta is a critical congenital heart defect.
- Infants with coarctation often have associated intracardiac anomalies, complicating surgical outcomes.
Purpose of the Study:
- To evaluate the surgical outcomes and long-term follow-up of infants undergoing coarctation of the aorta repair.
- To identify factors influencing survival and late complications in this pediatric population.
Main Methods:
- Retrospective review of 25 infants (<1 year) undergoing coarctation of the aorta repair between 1965-1982.
- Analysis of surgical techniques, associated anomalies, operative mortality, and long-term follow-up data.
Main Results:
- Twenty-one of 25 infants survived the initial operation.
- All operative deaths and three late deaths were associated with intracardiac anomalies.
- Two of 18 long-term survivors developed mild hypertension with residual gradients; others were in good health.
Conclusions:
- Surgical repair of coarctation of the aorta in infants can achieve good survival rates.
- Associated intracardiac anomalies are a significant determinant of both early and late outcomes.
- Long-term follow-up is crucial for managing potential complications like re-coarctation and hypertension.
Abstract:
Twenty-five infants under 1 year of age (mean weight 3.4 kg) underwent repair of coarctation of the aorta between the years 1965 and 1982. Three patients had coarctation only, three had coarctation with patent ductus arteriosus (PDA), and 19 had associated intracardiac anomalies. Eleven patients underwent resection of the aorta and end-to-end anastomosis. Eight had subclavian flap arterioplasty, five had patch graft arterioplasty, and one had subclavian-to-aortic anastomosis. Additional procedures were performed on seven patients: banding of the pulmonary artery on one, repair of total anomalous pulmonary venous drainage on one, mitral valve replacement on one, aortic valvotomy on one, and aortic valvotomy plus pulmonary artery banding on one. Twenty-one survived the operation. All patients who died had associated intracardiac anomalies. The 21 survivors have been followed from 3 months to 13 years, with three late deaths that were associated with intracardiac anomalies. Five of the survivors underwent additional second operations: one had repair of the re-coarctation, one had replacement of the prosthetic mitral valve, one had aortic valvotomy, and two had pulmonary artery debanding and closure of a ventricular septal defect. Two of the 18 surviving patients have mild hypertension associated with a residual gradient. The others are in good health.
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