System design considerations for laser angioplasty

Laser angioplasty, or the use of laser radiation to vaporize or remove obstructure atherosclerotic plaque, has been an active area of research for the past several years. This article reviews current design considerations for developing a safe, effective clinical laser angioplasty system. The choice of laser, fiber, and catheter determines the performance characteristics of such a system. The laser provides the power source for ablative radiation, the fiber furnishes a means of transmitting the laser radiation, and the catheter provides a way of directing the fiber at the target tissue. Other considerations, such as the need for feedback control of laser ablation and the planned application of the system in the coronary or peripheral circulation, also determine the ultimate design.