Quadricuspid aortic valve with centrally fenestrated leaflets causing aortic insufficiency
Related Experiment Video
Updated: Aug 23, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
W H Coltharp1, E T Warren, B J Heath
1Department of Surgery, Division of Cardiothoracic Surgery, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Abstract:
The occurrence of a quadricuspid aortic valve with single, central leaflet fenestrations causing aortic insufficiency has not previously been reported. We recently encountered these features during aortic valve replacement for severe aortic regurgitation in a 20-year-old man who had had a history of aortic insufficiency since age 2 years. The patient's late increase in symptoms was probably due to the fact that 1 of the 4 leaflets was somewhat flail, allowing incomplete coaptation and producing regurgitation over and above that caused by the central fenestrations.
Related Concept Videos
Aortic Regurgitation I: Introduction
Mitral Stenosis I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Valve Prolapse I: Introduction
Aortic Regurgitation III: Medical Management
Mitral Regurgitation I: Introduction
