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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
Coronary occlusion secondary to blunt chest trauma: a first attempt at balloon angioplasty
1The Department of Cardiac Surgery, Università di Genova, Ospedale San Martino, Genoa, Italy.
Insights
Blunt chest trauma can cause myocardial infarction (MI). Percutaneous transluminal coronary angioplasty (PTCA) failed in one case of coronary artery occlusion after trauma, but surgical repair led to a good outcome.
Area of Science:
- Cardiology
- Trauma Medicine
- Interventional Cardiology
Background:
- Transmural myocardial infarction (MI) from closed-chest trauma is rare, with few documented cases.
- Percutaneous transluminal coronary angioplasty (PTCA) has not been previously reported as a treatment for this condition.
Purpose of the Study:
- To report a case of anterior-wall myocardial infarction secondary to blunt chest trauma.
- To evaluate the efficacy of PTCA in treating coronary artery occlusion following blunt chest trauma.
Main Methods:
- A 40-year-old male patient with myocardial infarction post-blunt chest trauma underwent coronary angiography.
- The patient was treated with balloon angioplasty, followed by a second attempt, and subsequently surgical revascularization.
Main Results:
- Coronary angiography revealed isolated total obstruction of the left anterior descending coronary artery two months after trauma.
- Initial PTCA resulted in total reocclusion within 24 hours; a second attempt failed to restore patency.
- Surgical revascularization performed a week later resulted in the patient remaining asymptomatic a year post-injury.
Conclusions:
- PTCA, despite its initial failure in this case, may still be considered a treatment option for young patients with single-vessel coronary artery disease resulting from blunt chest trauma.
- Surgical revascularization proved effective in restoring patency and achieving a favorable long-term outcome in this patient.
Abstract:
There have been only 58 angiographically documented reports of transmural myocardial infarction due to closed-chest trauma. None of these cases has been treated by percutaneous transluminal coronary angioplasty. We report the case of a 40-year-old man who developed an anterior-wall myocardial infarction secondary to blunt chest trauma suffered in an automobile accident. Angiographic study performed 2 months after the injury revealed an isolated total obstruction of the left anterior descending coronary artery. The patient was judged a good candidate for balloon angioplasty, but total reocclusion occurred within 24 hours of the procedure and a 2nd attempt did not restore patency. Surgical revascularization was performed a week later. A year after his injury, the patient remains asymptomatic and is back at work. Despite the failure of percutaneous transluminal coronary angioplasty in its 1st application to coronary artery repair after blunt chest trauma, we believe it to be the treatment of choice in young patients and in single-vessel disease.
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