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An ideal ocular nutritional supplement?

Hannah Bartlett1, Frank Eperjesi

  • 1Neurosciences Research Institute, School of Life and Health Sciences, Aston University, Birmingham B4 7ET, UK. bartlehe@aston.ac.uk

Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
|July 2, 2004
PubMed
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This review identifies key antioxidants for ocular health supplements. Vitamins C and E, along with lutein and zeaxanthin, are recommended for preventing eye diseases like glaucoma and cataracts.

Area of Science:

  • Ophthalmology and Nutritional Science
  • Nutritional Biochemistry

Background:

  • Ocular diseases such as glaucoma, cataract, and age-related macular disease pose significant health concerns.
  • Nutritional supplementation is explored for its potential role in preventing the onset and progression of these conditions.
  • Risk factors include family history, smoking, poor nutrition, and excessive sunlight exposure.

Purpose of the Study:

  • To identify optimal antioxidants for an ocular nutritional supplement.
  • To guide supplementation for individuals at risk of or in early stages of ocular disease.

Main Methods:

  • Comprehensive literature search on Web of Science and PubMed.
  • Focused on studies investigating nutrients for ocular disease prevention and management.
  • Evaluated evidence for vitamins A, B, C, E, carotenoids (beta-carotene, lutein, zeaxanthin), minerals (selenium, zinc), and Ginkgo biloba.

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Main Results:

  • Conflicting evidence for vitamins A and E; B vitamins linked to reduced cataract risk; Vitamin C shows protective role in cataract prevention.
  • Lutein and zeaxanthin improve visual function in age-related macular disease.
  • Selenium supports antioxidant enzymes; Ginkgo biloba may benefit normal tension glaucoma patients.

Conclusions:

  • Vitamins C and E, lutein, and zeaxanthin are advocated for inclusion in an ideal ocular nutritional supplement.
  • These nutrients offer potential benefits for preventing and managing common ocular diseases.
  • Further research may clarify optimal dosages and combinations for specific conditions.