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Intussusception in neonates: analysis of 14 Japanese patients

I Ueki1, E Nakashima, M Kumagai

  • 1Department of Neonatology, St Mary's Hospital, Kurume University School of Medicine, Kurume, Japan. isaoeki@medikurume-uiac.jp

Journal of Paediatrics and Child Health
|July 2, 2004
PubMed

Insights

Neonatal intussusception is challenging to diagnose, especially in late-onset cases. Hypoxic events may be a key factor in the development of this condition in newborns.

Area of Science:

  • Neonatalogy
  • Pediatric Surgery
  • Gastroenterology

Background:

  • Intussusception is a significant cause of bowel obstruction in infants.
  • Neonatal intussusception presents unique diagnostic and etiological challenges compared to older children.

Purpose of the Study:

  • To elucidate the clinical characteristics and underlying causes of intussusception in neonates.
  • To differentiate between early-onset and late-onset neonatal intussusception.

Main Methods:

  • Retrospective analysis of 14 neonates diagnosed with intussusception from 1974 to 2001.
  • Categorization of patients based on symptom onset (first day of life vs. later).
  • Correlation of clinical signs with pathological findings.

Main Results:

  • Neonates with symptoms on day one frequently had intestinal atresia or malrotation (6/6).
  • Hypoxia was observed in 5 of 8 patients with symptoms developing within 24 hours of birth.
  • Diagnosis was particularly difficult in late-onset neonatal intussusception.

Conclusions:

  • Hypoxic events are implicated as a potential cause in the pathogenesis of late-onset neonatal intussusception.
  • Early diagnosis and recognition of associated anomalies are critical for managing neonatal intussusception.
Abstract

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