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Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
08:40

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy

Published on: August 1, 2013

[Preparation of dendritic cell tumor-vaccine with dendritic cells and problems in its clinical uses--review]

Zhi-Yong Yu1, Hu Chen, Kai Feng

  • 1Hematopoietic Stem Cell Transplatation Center, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100039, China.

Zhongguo Shi Yan Xue Ye Xue Za Zhi
|July 2, 2004
PubMed

Dendritic cell (DC), the most powerful antigen presenting cell, has been paid close attention to tumor immunotherapy. The tumor antigens were extracted by different ways to pulse DC, and then the mature DC were infused to patients to accelerate anti-tumor immuno responses. Its clinical use would provide a new therapeutic pathway other than surgical operation, irradiation, chemotherapy. In this paper, biological characteristics of DC, tumor-vaccine preparation and its clinical use were reviewed.

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