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Organizing pneumonia: perilobular pattern at thin-section CT.

Masuo Ujita1, Elisabetta A Renzoni, Srihari Veeraraghavan

  • 1Department of Radiology and Interstitial Lung Disease Unit, Royal Brompton Hospital, Sydney St, London SW3 6NP, England.

Radiology
|July 2, 2004
PubMed
Summary
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A perilobular pattern appears in over half of patients with organizing pneumonia on thin-section CT scans. This finding is common and aids in diagnosing organizing pneumonia.

Area of Science:

  • Radiology
  • Pulmonary Medicine
  • Medical Imaging

Background:

  • Organizing pneumonia is an idiopathic interstitial pneumonia.
  • Thin-section computed tomography (CT) is crucial for diagnosing lung diseases.

Purpose of the Study:

  • To characterize the appearance and frequency of a perilobular pattern in patients with organizing pneumonia using thin-section CT.
  • To determine the diagnostic significance of the perilobular pattern in organizing pneumonia.

Main Methods:

  • Retrospective review of thin-section CT scans from 21 patients diagnosed with cryptogenic organizing pneumonia.
  • Consensus review by two thoracic radiologists to identify and map CT abnormalities, focusing on the perilobular pattern.

Main Results:

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  • The perilobular pattern was observed in 57% of patients (12/21), often with multiple opacities.
  • Consolidation (95%) and ground-glass opacification (86%) were also common findings.
  • The perilobular pattern frequently abutted the pleura and was surrounded by aerated lung.

Conclusions:

  • The perilobular pattern is a frequent finding in organizing pneumonia, present in over half of cases.
  • This pattern complements other characteristic thin-section CT findings of organizing pneumonia.
  • The presence of the perilobular pattern can aid in the diagnosis of organizing pneumonia.