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Multifocal epithelioid hemangioendothelioma in bone
J B Krajca-Radcliffe1, R W Nicholas, J M Lewis
1Department of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock.
Summary
A rare epithelioid hemangioendothelioma (EHE) case in a 17-year-old
Area of Science:
- Orthopedic Oncology
- Vascular Tumors
- Pediatric Oncology
Background:
- Epithelioid hemangioendothelioma (EHE) is a rare, low-grade malignant vascular neoplasm.
- EHE can occur in various locations, including bone, with multifocal presentation being uncommon.
- Diagnosis and management of EHE require specialized oncologic and orthopedic expertise.
Observation:
- A 17-year-old male presented with refractory ankle pain.
- Imaging revealed multifocal lesions in the right ankle and foot bones.
- Biopsy confirmed grade I epithelioid hemangioendothelioma.
Findings:
- Multifocal epithelioid hemangioendothelioma of the ankle and foot is rare in adolescents.
- Advanced imaging (CT, MRI) is crucial for delineating lesion extent.
- Localized radiation therapy was the chosen treatment modality.
Implications:
- This case highlights the importance of considering rare tumors in adolescent lower extremity pain.
- Multifocal EHE requires careful staging and tailored treatment strategies.
- Further research into EHE's pathogenesis and optimal management is warranted.