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Paediatric myelography with iohexol.

L J Dube1, I G Blair, G Geoffroy

  • 1Department of Neuroradiology, Ste-Justine Hospital, Montreal, P.Q., Canada.

Pediatric Radiology
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

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Iohexol contrast media provides excellent visualization for paediatric myelography with no reported side effects. Higher iohexol concentrations may offer superior imaging, making it a safe option for pediatric patients.

Area of Science:

  • Radiology
  • Paediatric Imaging
  • Contrast Media

Background:

  • Myelography is a crucial diagnostic procedure in paediatric patients.
  • Iohexol is a non-ionic contrast agent used in various imaging modalities.
  • Evaluating the efficacy and safety of different iohexol concentrations in paediatric myelography is important.

Purpose of the Study:

  • To compare the visualization quality and safety of two iohexol concentrations (180 mgI/ml and 210 mgI/ml) in paediatric myelography.
  • To assess the diagnostic yield of computed tomography (CT) following myelography with iohexol.

Main Methods:

  • A prospective study involving 32 paediatric patients undergoing myelography.
  • Patients were randomized to receive either iohexol 180 mgI/ml (n=17) or iohexol 210 mgI/ml (n=15).

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  • Visualization quality, side effects, and vital signs were monitored. Additional diagnostic information from CT scans was recorded.

    • Main Results:

    • Excellent or good visualization was achieved in over 90% of patients receiving 210 mgI/ml iohexol and over 83% receiving 180 mgI/ml.
    • No significant side effects or alterations in vital signs were observed in either group.
    • CT scans provided additional diagnostic information in the majority of cases (14/18).

    Conclusions:

    • Both iohexol concentrations are safe and effective for paediatric myelography.
    • Iohexol 180 mgI/ml is suitable for routine use, while 210 mgI/ml may offer enhanced visualization without increased risk.
    • Effective procedural technique and patient communication likely contributed to the absence of adverse events.