Related Experiment Video
Updated: Aug 23, 2026

09:45
In Vivo Quantification of Protein Turnover in Aging C. Elegans using Photoconvertible Dendra2
Published on: June 13, 2020
Incontinentia pigmenti with NEMO mutation in a Turkish family
Fatma Silan1, Ilker Aydogan, Ayse Kavak
1Abant Izzet Baysal University, Duzce Medical Faculty, Medical Biology and Genetics Department, Dermatology Department, Duzce, Turkey. fsilan@ibuduzce-tip.edu.tr
International Journal of Dermatology
|July 3, 2004
Abstract
No abstract available in PubMed .
Related Concept Videos
Pedigree Analysis
Overview
Epistasis
In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
Pleiotropy
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
Genetic Lingo
Overview

