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Updated: Aug 23, 2026

Setup of Capillary Electrophoresis-Inductively Coupled Plasma Mass Spectrometry (CE-ICP-MS) for Quantification of Iron Redox Species (Fe(II), Fe(III))
Published on: May 4, 2020
Iron and ageing: an introduction to iron regulatory mechanisms
Cathy W Levenson1, Nadine M Tassabehji
1Program in Neuroscience and Department of Nutrition, Food and Exercise Sciences, 237 Biomedical Research Facility, Florida State University, Tallahassee, FL 32306-4340, USA. levenson@neuro.fsu.edu
Abstract:
While there have been significant advances made in our understanding of the cellular and molecular mechanisms that regulate iron absorption, transport, storage, and utilization, the effect of ageing on these mechanisms and the role of iron in the ageing process is not fully understood. Thus, this review will provide an overview of the iron regulatory mechanisms that may be a factor in the ageing process. Additional reviews in this volume represent an attempt to explore the very latest information on the regulation of iron with a particular emphasis on age-related pathology including mitochondrial function, Parkinson's disease, Alzheimer's disease, stroke, and cardiovascular disease.
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