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Updated: Aug 19, 2026

Microdissection of Black Widow Spider Silk-producing Glands
Published on: January 11, 2011
Use of antivenin to treat priapism after a black widow spider bite
Nancy G Hoover1, James D Fortenberry
1Division of Critical Care, Children's Healthcare of Atlanta at Egleston, Atlanta, Georgia 30322, USA.
Abstract:
Black widow spider envenomation (BWSE) is commonly associated with severe abdominal pain, muscle cramping, and hypertension. Treatment is primarily symptomatic with the use of opiates and benzodiazepines. Priapism is a complication of BWSE that has only rarely been reported. We describe a 17-month-old male who developed priapism after known BWSE. His priapism did not respond to opiates or benzodiazepines, and he was treated with black widow spider antivenin. Complete detumescence followed within several hours. The patient required no additional opiates for pain and was discharged from the hospital the following day. The patient's rapid improvement after antivenin suggests its efficacy in treating BWSE-associated priapism.
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