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Updated: Aug 23, 2026

Establishing a Diaphyseal Femur Fracture Model in Mice
Published on: December 9, 2022
Development of an animal model of acetabular fractures
Steven A Olson1, Edward A Connolly, Scott Smith
1Department of Surgery, Duke University Medical Center, Durham, NC, USA. Olson016@mc.duke.edu
Abstract:
A closed intraarticular fracture is a complex injury that consists of a physical disruption of the subchondral bone and articular surface, and an impaction injury to the articular surface that occurs at the time of the fracture. Few experimental models have been able to incorporate the elements of displaced articular fractures and blunt impaction injury to the articular surface. This work details the initial stages of an attempt to develop such model. Using a model of a dorsal wall fracture of the acetabulum in a goat, we have developed a bench-top method for assessing articular contact stress. Additionally, preliminary in vivo survival data are presented.

