Related Experiment Video

Updated: Aug 23, 2026

Conditional Knockdown of Gene Expression in Cancer Cell Lines to Study the Recruitment of Monocytes/Macrophages to the Tumor Microenvironment
10:59

Conditional Knockdown of Gene Expression in Cancer Cell Lines to Study the Recruitment of Monocytes/Macrophages to the Tumor Microenvironment

Published on: November 23, 2017

Altered surface expression patterns of circulating monocytes in cancer patients: impaired capacity of T-cell

Selma Ugurel1, Monika Lindemann, Dirk Schadendorf

  • 1Skin Cancer Unit, German Cancer Research Center, and Department of Dermatology, University Hospital of Mannheim, Theodor-Kutzer-Ufer 1, 68167, Mannheim, Germany. s.ugurel@dkfz.de

Cancer Immunology, Immunotherapy : CII
|July 3, 2004
PubMed
Abstract

No abstract available in PubMed .

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...