Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

MURCS association and hypothalamic anovulation.

J Pablo Méndez1, M Orozco, A Iván Ruiz

  • 1Departamento de Biología de la Reproducción, Instituto Nacional de La Nutrición Salvador Zubirán, México, D.F.

Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinicopathological predictors of cervical lymph node metastases and disease persistence in pediatric papillary thyroid carcinoma: A single-center cohort study.

Journal of pediatric surgery·2026
Same author

Postbiotic Dietary Supplementation with Sonicated Shewanella sp. SpPdp11 Improves Intestinal Status in Juvenile Senegalese Sole (Solea senegalensis).

Marine biotechnology (New York, N.Y.)·2026
Same author

Bimanual uterine flexion maneuver during transvaginal sonography: optimizing the endometrial angle of insonation.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2026
Same author

Repair of Resin Composite Restorations: An Umbrella Review of Systematic Reviews.

Operative dentistry·2026
Same author

ASO Visual Abstract: Targeted Preoperative Nutritional Support Within an Enhanced Recovery After Surgery Program for Malnourished Colorectal Cancer Patients: Postoperative Outcomes Comparable to Well-Nourished Patients in a Prospective Single-Center COHORT.

Annals of surgical oncology·2025
Same author

Genetic and clinical landscape of Duchenne muscular dystrophy in Guatemala: insights from a national study.

Frontiers in genetics·2025

This study reports a case of MURCS association, identifying hypothalamic chronic anovulation. Early endocrinological evaluation is crucial for managing potential secondary disorders in these patients.

Area of Science:

  • Reproductive Endocrinology
  • Developmental Biology
  • Genetics

Background:

  • MURCS association is a rare congenital condition characterized by mullerian duct aplasia, renal aplasia, and cervicothoracic somite dysplasia.
  • Endocrine dysfunction, particularly hypothalamic amenorrhea, can be associated with MURCS association, impacting reproductive health.

Observation:

  • An 18-year-old female patient with MURCS association presented with hypothalamic chronic anovulation.
  • Hormonal assays (PRL, TSH, GH, E, F) were within normal adult female ranges, with normal responses to TRH and ACTH stimulation tests.
  • Gonadotropin levels (LH, FSH) showed dissociation, and LHRH stimulation tests indicated impaired pituitary response, confirming hypothalamic chronic anovulation.

Findings:

  • The patient exhibited persistent follicular phase progesterone levels, indicative of anovulation.

Related Experiment Videos

  • Ovulation was successfully induced with clomiphene citrate, confirming the diagnosis of hypothalamic chronic anovulation.
  • This case highlights the importance of comprehensive endocrinological assessment in patients diagnosed with MURCS association.

    • Implications:

    • Early and thorough endocrinological evaluation is essential for patients with MURCS association to detect and manage potential secondary reproductive disorders.
    • Understanding the spectrum of endocrine abnormalities in MURCS association can guide timely interventions and improve patient outcomes.
    • This case underscores the complex interplay between congenital malformations and hormonal regulation, necessitating a multidisciplinary approach to patient care.