Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Targeting plasmid-encoded proteins to the antigen presentation pathways.

Jens A Leifert1, Maria P Rodriguez-Carreno, Fernando Rodriguez

  • 1Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Immunological Reviews
|July 6, 2004
PubMed
Summary

DNA vaccines offer a flexible platform for manipulating antigen presentation pathways to create targeted immune responses. This review explores strategies for designer immunity using DNA vaccine technology.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Automatic framework for PD-L1 expression evaluation in Latino patients with non-small cell lung cancer.

Journal of pathology informatics·2026
Same author

Stage III Non-small Cell Lung Cancer Resectability in a Country With Limited Diagnostic and Therapeutic Resources: A Colombian Expert Consensus.

Cancer control : journal of the Moffitt Cancer Center·2026
Same author

Distinct cytotoxic cell subsets underlie protective and non-protective immunity to African swine fever virus.

Emerging microbes & infections·2026
Same author

Metagenome-assembled genomes from biological soil crusts in sandy sediments of Kitty Todd Nature Preserve, OH, USA.

Microbiology resource announcements·2026
Same author

Adjuvant-induced macrophage activation compromises BA71ΔCD2-mediated protection against African swine fever virus.

NPJ vaccines·2026
Same author

Fish welfare in a changing world: New developments and current challenges.

Journal of fish biology·2026

Area of Science:

  • Immunology
  • Vaccinology
  • Molecular Biology

Background:

  • Antigen presentation pathways are critical for adaptive immunity.
  • Targeting these pathways could enable the development of tailored immune responses.
  • DNA vaccines provide a versatile tool for exploring such strategies.

Purpose of the Study:

  • To review strategies for manipulating antigen presentation pathways using DNA vaccines.
  • To discuss the mechanisms underlying the success of these targeting strategies.
  • To highlight the potential of DNA vaccines for inducing designer immune responses.

Main Methods:

  • Review of existing literature on DNA vaccine technology.
  • Analysis of various targeting strategies for antigen presentation.

Related Experiment Videos

  • Discussion of potential mechanisms of action.

    • Main Results:

    • DNA vaccines are rapidly constructed and easily modified.
    • Various strategies exist for targeting antigen presentation pathways.
    • The mechanisms of success for these strategies are still under investigation.

    Conclusions:

    • DNA vaccines are promising for developing designer immune responses.
    • Further research is needed to fully understand the mechanisms involved.
    • Targeting antigen presentation pathways holds significant potential for immunotherapy.