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Incidence of acute endophthalmitis after triamcinolone-assisted pars plana vitrectomy

Taiji Sakamoto1, Hiroshi Enaida, Toshiaki Kubota

  • 1Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Science, Sakaragaoka 8-35-1, Kagoshima 890-8520, Japan. tsakamot@m3.kufm.kagoshima-u.ac.jp

American Journal of Ophthalmology
|July 6, 2004
PubMed
Abstract

Insights

Acute endophthalmitis is rare following triamcinolone acetonide-assisted pars plana vitrectomy (PPV). This study found a very low incidence of infection, suggesting triamcinolone use during PPV is not a significant risk factor.

Area of Science:

  • Ophthalmology
  • Surgical Innovation

Background:

  • Pars plana vitrectomy (PPV) is a common surgical procedure.
  • Triamcinolone acetonide is sometimes used adjunctively during PPV.

Purpose of the Study:

  • To determine the incidence of acute endophthalmitis after triamcinolone acetonide-assisted PPV.
  • To assess the safety of intraoperative triamcinolone use in PPV.

Main Methods:

  • Retrospective analysis of 1,886 cases undergoing triamcinolone-assisted PPV.
  • Data collected from seven academic clinical centers over 23 months (Jan 2002 - Nov 2003).

Main Results:

  • One case (0.053%) of acute endophthalmitis was reported, caused by Staphylococcus epidermidis.
  • No other instances of postoperative endophthalmitis were observed.

Conclusions:

  • Intraoperative triamcinolone acetonide during PPV does not appear to be a significant risk factor for acute endophthalmitis.
  • The findings support the safety of using triamcinolone acetonide in conjunction with PPV.

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