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[Symptomatic rickets in adolescents].

E Mallet1, J Gaudelus, P Reinert

  • 1Département de pédiatrie médicale, CHU de Rouen, France. Eric.mallet@chu-rouen.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|July 6, 2004
PubMed
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Rickets, a bone disease, affects adolescents, particularly those from immigrant families, due to insufficient calcium and vitamin D. Early detection and treatment with calcium and vitamin D are crucial for recovery.

Area of Science:

  • Pediatrics
  • Nutritional Science
  • Bone Metabolism

Background:

  • Adolescence is a critical growth period with increased risk for nutritional deficiencies.
  • Calcium and vitamin D insufficiency are prevalent in adolescents, impacting bone health.
  • Rickets, though debated for supplementation, is a recognized pathology in this age group.

Purpose of the Study:

  • To evaluate the frequency of rickets in adolescents.
  • To define risk criteria for adolescent rickets.
  • To characterize the clinical and radiographic presentation of adolescent rickets.

Main Methods:

  • Retrospective analysis of 41 hospitalized adolescents diagnosed with rickets between 1985 and 2000.
  • Data collection included patient demographics, geographic origin, clinical symptoms, laboratory values (serum calcium, 25-hydroxyvitamin D), and radiographic findings.

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  • Treatment protocols involving calcium and vitamin D supplementation were reviewed.

    • Main Results:

    • The study identified 41 cases of rickets in adolescents, predominantly from immigrant families and Northern France.
    • Affected adolescents presented with lower limb pain, deformities (genu valgum), muscle spasms, or tetany.
    • Low serum calcium and extremely low 25-hydroxyvitamin D levels were consistently observed, alongside characteristic radiographic metaphyseal changes.

    Conclusions:

    • Rickets is not frequent but under-diagnosed in adolescents, posing a significant risk, especially for immigrant populations.
    • Adolescent rickets is linked to rapid growth, inadequate calcium and vitamin D intake.
    • Prompt diagnosis and combined calcium and vitamin D treatment, including intravenous administration for hypocalcemia, are essential.