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Case report 751: Spindle cell lipoma causing marked bone erosion.

I J Braunschweig1, I H Stein, M I Dodwad

  • 1Department of Radiology, Monmouth Medical Center, Long Branch, New Jersey 07740.

Skeletal Radiology
|January 1, 1992
PubMed
Summary
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Spindle cell lipoma, a rare tumor, can cause significant bone erosion, particularly in unusual locations like the foot. This case highlights the diverse presentations of this benign soft tissue neoplasm.

Area of Science:

  • Orthopedic Surgery
  • Surgical Pathology
  • Oncology

Background:

  • Spindle cell lipoma (SCL) is a benign soft tissue tumor characterized by mature adipocytes and a proliferation of spindle-shaped cells.
  • Typically found in the subcutaneous tissue of the neck and shoulders in middle-aged men.
  • SCLs are generally slow-growing and asymptomatic, often presenting as soft, mobile masses.

Observation:

  • An unusual case of spindle cell lipoma presenting in the foot is described.
  • The foot lesion exhibited marked bone erosion, an atypical feature for this type of tumor.
  • Radiographic and histological examination confirmed the diagnosis of spindle cell lipoma.

Findings:

  • Spindle cell lipoma can present with aggressive local behavior, including bone destruction.

Related Experiment Videos

  • The histological hallmark of SCL is the presence of bland spindle cells admixed with mature fat cells.
  • Immunohistochemical analysis typically shows positivity for CD34 and/or CD99.

    • Implications:

    • This case expands the known clinical and radiological spectrum of spindle cell lipoma.
    • It emphasizes the importance of considering SCL in the differential diagnosis of foot masses, even with atypical features like bone erosion.
    • Accurate diagnosis is crucial for appropriate management and to avoid unnecessary aggressive treatment.